Impossible! Outside of gene drives (which sound a little dangerous...), I really want to do some simple CRISPR projects (I have a specific idea in mind; although not for hacker news ;). Too bad you need a lab, even if it's probably a good idea to limit hobbyists.
the non-native bees shipped around the country (US) and that are the primary pollinators in agriculture appear to already be fairly resistant to neonics.
I'm sure there won't be any negative consequences ;)