[pgib]

The Amazon Certificate Manager uses SNI, and you can request certificates with multiple hosts and even wildcard domains. I would imagine if you upload your own multi-domain certificate that it would work in the same way, but I have never tested that.

[imperalix]

I think you mean SAN instead of SNI. SNI is like host headers for TLS connections, while SAN on certs allow you have to very valid for multiple names.