Most of the time I use GtkD because my target platform is mainly linux but if I also want to target windows I use DlangUI. Don't actually target OSX but the apps happen to work on there too.
Great. Any comments on GtkD vs. DLangUI, in terms of ease of use, features you need, look-and-feel on the different OSes, etc.? Planning to write a few small GUI apps in D to try it out as a platform for that. Mine will be only on Linux and Windows, though, since I don't have a Mac.
For the web backends I always use vibe.d