[spotman]

Your absolutely correct that it is not risk free, however, if you do not use foreign keys (which no huge scale mysql install like schemaless does) and you know what your doing (read: calculating the expected load, adding throttles and sanity checks, backups, etc) online alters are extremely feasible with mysql and folks have been doing them for years.

I know first hand shops like FB use a similar method in production.

Also, big note, the whole point of "schemaless" (And other things, like fb's friend feed architecture) is that you don't make schema changes.