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by skylark 3625 days ago
IQ has the highest genetic correlation out of any trait we've observed in Psychology - r ~ 0.7 if I recall correctly from my college days.
1 comments

This is actually interesting in terms of GWAS - there used to be a large difference between "heritability" (~the measurable variance offspring shares with their parents, like height in cm, which can be influenced by a ton of parameters if you don't know about them/don't control them [like nutrition]). In the age of genome-wide association studies the linked SNPs often correlate much weaker than the heritability predicts (example: you could explain 10% of variance with SNPs, but heritability says it should be 70%) - this was called the problem of "missing heritability".

Some more complex models recover some of that missing heritability, these slides are a nice summary: http://jvanderw.une.edu.au/Mod9Lecture_SNP_Her.pdf

There is a paper from 2011 looking at human intelligence (http://www.nature.com/mp/journal/v16/n10/full/mp201185a.html) and using a little bit of modeling they got the correlation up high:

>We estimate that 40% of the variation in crystallized-type intelligence and 51% of the variation in fluid-type intelligence between individuals is accounted for by linkage disequilibrium between genotyped common SNP markers and unknown causal variants.

However, look at that "unknown", because the same abstract says:

>Finally, using just SNP data we predicted ~1% of the variance of crystallized and fluid cognitive phenotypes in an independent sample.

Using their SNPs alone it's only 1%. I assume the "true" genetic variability (~~~heritability) is somewhere in between those two values, since the 40/50% number seems to assume that these unknown variants will be discovered (they haven't yet AFAIK, maybe they don't exist, maybe they do).