One of the last consumer-facing, blockbuster level startups outside of SV (or California) that comes to mind was Groupon. But I don't consider them to be that great; kind of a fad that took off for a while and is now lingering. When I say blockbuster level startup I mean something that becomes a household name used by mostly consumers. Highly visible companies mostly. I lump LA/SV together because they're in the same state, and there seems to be a lot of inter-funding between the two areas. But I'm also from Chicago so maybe it's just me. Hah.