[walden42]

Assuming all assets get stored on S3, the other common writing scenario is logging. How would multiple machines writing to the same log file work?

[Corrado]

Generally, you wouldn't write to the same log file. Prepending/Appending the instance name to the file would be enough to make it unique.

[jabl]

It wouldn't. NFS is not fully POSIX compliant, largely due to not being cache coherent. In particular, O_APPEND is not supported.