[mistersquid]

Add grep whitelist to your spam filter for some arbitrary extension, e.g. a tld such as '.com'.

This way the address can be [e-mail], you can whitelist *.com@ (or higher up on the subdomain if necessary).

Not sure if this would maintain the efficiency of your (or any) spam filter, but it does avoid the '+' character.

[bronson]

In my experience adding the domain of the recipient often leads to problems.

  Rep: "Can you verify your email address?"
  Me: "er, [e-mail]"
  Rep: "Hey, I didn't know you worked for Verizon!"
  Me: "no..."

And now the call gets excruciatingly slow and unfriendly because the rep thinks I'm trying to hack something.

Also, more than one web forum has silently binned me until I removed the domain from my email address. Had one where I could post for a few days, then the admin deleted me and sent that email address a crazy anti-spam rant thinking I was a bot.

I still like using unique email addresses but I make sure they're obscure.

[dreamcompiler]

I use the domain backwards e.g. [e-mail] service agents don't notice, and it's easy for me to tell where the email was supposed to have originated.