If you're not spending every minute of your life trying to get laid, how is that not as bad as standing by and letting innocents die? Every choice you make has an impact on the life of your (or someone else's) hypothetical future offspring. Is fighting poverty tantamount to genocide? Richer societies tend to have less children and healthier children on average - which means disproportionately less of the certain kind of people that suffer from various poverty-related diseases.
Doing moral calculations on people who have not yet been conceived is tricky, and you can't simply equate them with living and breathing ones.
can you answer the converse? It's not at all clear to me how excising genetic dead ends is anything even remotely related to murder or sterilization, so I feel like the burden is on you to actually put something forth.
Under that argument - choosing not to mate is erasing people from the gene pool. Choosing who you mate with is also erasing people from the gene pool and denying people the possibility of mating with you at all is also erasing people from the gene pool. With the safe assumption that sperm and eggs have variations from one another - masturbating erases thousands if not millions of potential people from the gene pool and every period a female has without fertilization is another person missing from the gene pool.
Given the number of people on the planet - resulting in trillions (and trillions) of DNA combinations between mating pairs - millions of possible people are erased from the gene pool on the grounds of "not everyone can mate with everyone in a given lifetime, even if we wanted to". Not to mention all the potential genes that die each day.
When a couple uses gene therapy to ensure their children don't get stuff like mitochondrial myopathy, how is that bad?
Do you really think it's better for that couple (and society) that they do it the "natural way" and only have children who won't live to see their eighteenth birthday?
The issue cannot be as absolute as you have framed it. For example, laws agains consanguinity (having a child with a close relative) "prevent certain kinds of people from even being born".
Doing moral calculations on people who have not yet been conceived is tricky, and you can't simply equate them with living and breathing ones.