Having offline apps is game changing because not everyone has access to the Internet all day long, and doing tasks like image and video editing on your laptop will be much easier and faster than using web services.
You can already side-load Android apps on ChromeOS, as well as with Chrome on other platforms. All you need is the ArcWelder chrome extension, which I'm pretty sure is provided by google themselves, to package up an apk into a chrome app: https://chrome.google.com/webstore/detail/arc-welder/emfinbm...
If it's get too affordable with a low-end hardware, most users will still opt for LAN cafe which is popular in China and some countries and is cheapest option for gaming and surfing Internet.
This is not game changer. It is exciting and might help grow the Android ecosystem. I just hope Google learned from the Honeycomb fiasco.