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by patrickmclaren 3686 days ago
Agreed. One might say to take the conclusion with a grain of salt, but "next to useless" is being overly dismissive.
1 comments

No, it is simply a statement of fact. Given that all treatments for depression produce a powerful placebo effect, any non-placebo-controlled trial tells you absolutely nothing about the effectiveness of the treatment. It's true that it does tell you if the treatment is safe, but I think it's fair to say that that information is "next to useless", as there are an almost infinite number of potential treatments. The only way to know if any of them are effective is to do a placebo-controlled trial.

Still, I think it is a plausible treatment, so hopefully there will be some better trials.