[brianwawok]

Twitter still seems a more interesting company than most startups I read about across the pond. I can't think of the last say UK based startup that drastically changed my life. I am sure they exist, but I can't think of one right now...

[PeterisP]

If you're looking from an investor point of view (the audience for different profitability metrics) then even the most vague measure of profitability is more relevant than whether it drastically changes the life of users - it you would want that, then you'd look for the charities with most impact per dollar instead of gifting that money to finance the burn rate of an unprofitable (but interesting) tech startup.