Depends CA is quite liberal in terms of non competes and I suspect they woudl argue that self driving trucks is sufficiently different from self driving cars.
This is one reason why California is great for tech workers, the unenforceable non-competes. In much of the country you'd have to wait out a year before working in the same industry as your current employer.
Agreed the USA having 52 separate sets of employment laws does not make sense - really employment law should be done at federal level - think of the saving in reduction in red tape.
Though I suspect HR and Lawyers might lobby against that as a job protection scheme.