[ttctciyf]

Interesting to compare Frank Herbert's Destination: Void:

The crew are just caretakers: the ship is controlled by a disembodied human brain, called "Organic Mental Core" or "OMC", that runs the complex operations of the vessel and keeps it moving in space. But the first two OMC's (Myrtle and Little Joe) become catatonic, while the third OMC goes insane and kills two of the umbilicus crew members. The crew are left with only one choice: to build an artificial consciousness that will enable the ship to continue. The crew knows that if they attempt to turn back they will be ordered to abort (self destruct).

https://en.wikipedia.org/wiki/Destination:_Void