[patall]

I think you underestimate the immune system. We automatically remoce thousands of misfolded proteins every second in our cells. Its just those few the cellular defence has not yet adapted to too much that we notice. Some kinds of vaccination might work (like expressing part of the misfolded protein to make it an antigen) etc. The reason why we do not have any medication against prions is because they have never been a big thread to us. Pretty much like asteroids, if they fell on us regulary, we would build a planetary defense. But for now, that not up on the agenda