[biggerfisch]

I much prefer tmux because it really doesn't matter what system I'm on, I can easily rearrange windows/panes and form a custom workspace. While iTerm can do this on the local mac, it's a real pain to use tabs/splits in it over SSH. Plus, like others mentioned, tmux stays alive.

I also just prefer the interface of tmux. You can completely configure your status bar as well, and I find that really useful. For example, my status bar [1] has my current music, host, time in the two timezones I care about, and load. I also use a commandline chat client for work that I can embed into a tmux pane and never have to switch away from iTerm to communicate.

[1] http://i.imgur.com/XrKtV7J.png