Hacker News new | ask | show | jobs
by liviu- 3738 days ago
Could you please elaborate for those unfamiliar with their community?
1 comments

It's tricky to pinpoint exactly when modern "bioinformatics" started. Some notable times are 1979 when the Los Alamos Sequence Database started, 1982 when that became GenBank, and certainly by 1990 when the Human Genome Project started.

GenBank is "an open access, annotated collection of all publicly available nucleotide sequences and their protein translations" (https://en.wikipedia.org/wiki/GenBank ). Most journals now require that sequences be entered into GenBank before publication.

I'll add a few historical observations. The early work at Los Alamos was on Sun machines running Sybase (1987, according to https://en.wikipedia.org/wiki/Sybase ). These are serious Unix fans, who quickly took to perl when it came out. I think some of the support for SybPerl came from bioinformatics; the SybPerl, OraPerl, and other *Perl systems helped create the extension system for perl5. (I am not able to verify that, though the author of SybPerl, Michael Peppler, consulted in the mid-1990s for "Research Genetics" http://www.peppler.org/resume.html .)

Unix people in the early 1990s were serious perl fans. The most popular perl4 library for CGI programming was cgi-lib.pl, by Steven Brenner, a computational biologist/bioinformatics researcher. It was replaced in perl5 by CGI.pm, by Lincoln Stein, another bioinformatics researcher.

This gives a hint that bioinformatics has not only a close connection to the technologies needed for the first dot-com era, but also that the field itself tends towards open resources.

("Tends towards" != "always". See point #3 of https://liorpachter.wordpress.com/2015/07/10/the-myths-of-bi... .)