[msl]

The flight computers on any manned NASA spacecraft have not been made by HP. The Gemini capsules and the Space Shuttle used IBM computers [1,2] and Apollo used computers made by MIT (primary computers) and TRW (Abort Guidance System) [3]. I could also not find any information on a mission that failed in such a way.

[1] http://history.nasa.gov/computers/Ch1-2.html

[2] http://history.nasa.gov/computers/Ch4-3.html

[3] http://history.nasa.gov/computers/Ch2-8.html