[compactmani]

The issue I see with changing so many alleles is that we may not know all of the phenotypic consequences of each allele. Moving 10,000 alleles to the best intelligence settings might make people smarter, but genes are highly pleiotropic. Mutating 10,000 genes could have 10,000 phenotypic side effects.

How do you optimize: maximize intelligence subject to not messing up the organism too much. How would you do this for multiple phenotypes? Maximize height and intelligence subject to not messing up the organism too much.