I just tried this and I am not happy with it. I dislike the extreme changes it makes to HN's layout and colors. Way too heavy handed for me. Surprising, given the name, which is obviously a play on Reddit Enhancement Suite, which is a great addon that doesn't make reddit look totally different.
The extension badly needs settings, so that you can control what features you want and don't want. That being said, the author of the extension isn't really active on GitHub. He certainly hasn't replied to my pull request that adds the ability to tag users yet.
I might fork it one day, call it HNES+ or something. Then maybe development can gain a bit of traction again.
I use "HN Special"[1] with the visual theme turned off (it irritates me). It also offers infinite scrolling, although it makes accessing the search box a little tedious.
Just tried it, this IMO is definitely an improvement over the Hacker News Enhancement Suite, especially when using the default HN style.
However, I frequently use HN without scripts and cookies, and I find it somewhat disappointing that it uses cookies to store its settings instead of local storage.
I'll open an issue on the repo when I find the time though.