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by marckemil 3780 days ago
Never heard of it before. That group seems to have published a phase II trial so I would assume they'd be looking at a phase III.

I always look at "promising results" with skepticism, especially when the authors have a direct financial interest in the project.

To keep in mind: complete remissions and partial remissions are good, but they're "softer" outcomes. What we want to see is an impact on "harder" outcomes, mainly overall survival. Cause-specific survival is another good one.

We like to associate tumor shrinkage with better survival but it's not that simple (unfortunately). Do we kill people with our treatment? It shrinks the tumors, but for how long? Is the treatment convenient? How did they define "partial response"? What tool did they use? -- the list goes on.