[Joky]

This seems to me to be very close to what Pythran [0] is doing (since 2011), except that Pythran includes some type inference and bridge with Python code.

So view through that lens I'm not really seeing the novelty right now?

[0]: http://github.com/serge-sans-paille/pythran/

[anon4]

There is also nuitka - http://nuitka.net/