Hacker News new | ask | show | jobs
by fallingfrog 3815 days ago
I feel like this article is misleading in some of the details, for example some of the neurons that are quieted are inhibitory neurons, so the net effect is to make other neurons more activated.
1 comments

The notion that some of the neurons silenced by alcohol are inhibitory neurons is actually the explanation that researchers have proposed for why stimulating glycine receptors produces an increase in dopamine release. The idea which is shown in a diagram in the article is that silencing GABA-releasing interneurons (which are inhibitory) with glycine consequently disinhibits dopaminergic neurons.