[ggreer]

It's a software setting, though the setting varies in each OS. OS X has my favorite layout: Dvorak with qwerty shortcuts. That gives me normal placement for cmd + x/c/v/etc.

I really like Dvorak. I don't type much faster, but typing requires much less effort. If you know someone who types Dvorak, take a look at the wear patterns on their keyboard. It's pretty much the home row. Contrast that to qwerty, where the top row (especially the E key) gets an inordinate amount of wear.