[Gatsky]

In my opinion, Holmes is a fanatic. This is subtly different from being fanatical or obsessive about certain things, which is probably a good or even necessary characteristic for a founder. She seem to just be a fanatic. She has found a mission, and is pursuing it without any second thoughts. Never mind whether anybody else thinks that the mission is actually that important... Fanatics have the ability to impress those close to them, because of their overriding zeal. From a distance though, they seem crazy and somewhat deficient human beings.

I'm not sure that fanatics do science well, or handle other people's money that well either....