Not only is it acceptable, it is necessary. How do you think our ancestors determined what was safe to eat? As the saying goes, sometimes you need to break some eggs. Now don't get me wrong, I'm neither condoning, nor encouraging, wanton negligence concerning human safety, obviously all possible efforts should be made to ensure it, but sometimes, such as in cases like this, the rewards far outweigh the risks.
Yes. And thousands have died in death camps to bootstrap our modern cariology. We should be grateful to all people who died in the past providing us data and knowledge, and to honor them we should use it in the best way we can, so that no one else has to die.