[TeMPOraL]

I think the biggest advantage Big Pharma would have over the cartels and fly-by-night drug makers is that legitimate companies are held accountable to quality and safety standards, therefore you can be sure that you're buying a drug produced following a proper process and contains only what it's supposed to. A lot of deaths from (illegal) drug use is caused by impurities and not by the drug itself, and illicit actors don't have incentives to reduce them.