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by eurokc98 3897 days ago
While this comment is funny, it's also arrogant and incorrect. It's not fair to indict folks trying to change lives based on what's needed to drive pageviews, ie attention grabbing headlines.

30 seconds of research provides a pretty obvious connection, regardless of your "no fucking clue what they're doing" accusation...

Nilotinib is a Tyrosine Kinase Inhibitor https://en.wikipedia.org/wiki/Nilotinib

Tyrosine kinase inhibitors regulate serotonin uptake in platelets http://www.ncbi.nlm.nih.gov/pubmed/7589171

Tyrosine kinase in serotonin induced cerebral constriction http://www.ncbi.nlm.nih.gov/pubmed/9472895

It's apparent that Nilotinib plays a role with Serotonin, which is of course implicated in Parkisons and many other neurological disorders, but I guess we are hung up on cute headlines and not the real story. http://phys.org/news/2010-06-serotonin-decades-old-mystery-p...

[edit:sp]

1 comments

Also, drug repurposing is often a highly data-driven field. So it may not involve predictions where there's a high degree of certainty, but data-driven methods can shift a 1 in a million (or more) chance of success into a 1 in 3 or 1 in 5. Such wins are absolutely huge.