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by apl 3906 days ago
The key bottleneck with all connectome projects is still reconstruction. There's on the order of a hundred billion neurones in the human brain; they're connected via 1,000-10,000 times the number of synapses. Current machine learning approaches are decent, but still require massive amounts of proof-reading.

Circuit neuroscience in Drosophila or the mammalian retina suggests neurones and synapses are indeed the level of detail we'll need in order to gain insight into computational mechanisms. So we're a long, long way off -- don't be too impressed by this particular dataset (which is insanely coarse!).

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Hey if you guys want to help out with the proof reading effort, we've got a cool dataset that has a resolution of 16.5 nm x 16.5 nm x 23 nm at http://eyewire.org ^_^