[psycr]

Are you referring to string-overlap graphs for de novo assembly? In that case, isn't CRISPR addressing another problem?

[akulesa]

I think Gatsky is referring to the method described here:

http://www.technologyreview.com/news/537916/rebooting-the-hu...

[Gatsky]

https://ccb.jhu.edu/software/hisat2/index.shtml