[mellery451]

Here are some of my reasons for running tmux inside of iTerm:

* easy layout of panes (windows) in fullscreen mode. I have tmux macros setup to quickly get different pane layouts -- e.g. 65% left, then two vertical split panes in the remaining right 35%. Typically I run vim in the larger pane and then have two other panes for various other CLI stuff on dev systems. I have a number of other preconfigured layouts depending on what I'm trying to get done.

* tmux session can be detached/reattached. I've on occasion had iTerm crash or I've accidentally quit it (cmd-Q). With tmux, my session is still running, so I just restart iTerm and reattach...everything back where I left off. There is even a new-ish plugin for tmux that lets you save tmux sessions so that you can restore after restart. The reattaching also makes it low-overhead if/when iterm wants to update itself (admittedly rare).

* Once you get used to tmux navigation keys/commands, they will conceptually work on linux systems as well if you run tmux (more portable muscle memory).

just my $0.02