[PaulHoule]

There's the problem that with 5 events you can't know if it was a fluke and also the subpopulation that you are sampling from.

I think for instance how the drug Naltrexone seems to work very well for treating alcoholism in Asians and poorly in Blacks. If you don't take this into account whatever result you get is going to indicate that the drug is too effective or not effective enough.