[kingmanaz]

>Good for mindset, but bad for soulset.

Exactly. From the linked article: Modafinil "indirectly upregulates cerebral serotonin" ...a concern for those focusing on quality of life rather than quantity of output.

"To give you some perspective: the type of behavior displayed by upper classes of society; the elegance, the subtlety, the higher levels of intelligence and conscience, most likely reflect low serotonin levels (or rather, a lower ratio of serotonin to other neurotransmitters). Now take the opposite, high serotonin, say in combination with a poor immune system, low metabolic rate, chronic inflammation, and what will you have? Well, a serf/thrall."

Further discussion here:

http://www.longecity.org/forum/topic/73104-natural-serotonin... http://www.longecity.org/forum/topic/78451-symptoms-signs-of...