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1.
CRISPR tech selectively shreds cancer cells, including "undruggable" cancers (innovativegenomics.org)
600 points by gmays 7 hours ago | 159 comments
2.
Swift at Apple: Migrating the TrueType hinting interpreter (swift.org)
78 points by DASD 2 hours ago | 31 comments
3.
How to setup a local coding agent on macOS (ikyle.me)
193 points by kkm 5 hours ago | 61 comments
4.
Malware developers added nuclear and biological weapons text to to their spyware (twitter.com)
242 points by marc__1 1 day ago | 165 comments
5.
Pirates, a naval warfare game inspired by Sid Meier's Pirates (piwodlaiwo.github.io)
156 points by iweczek 5 hours ago | 67 comments
6.
Congress Just Rushed Through a Disastrous Copyright Office Overhaul (eff.org)
46 points by Cider9986 1 day ago | 2 comments
7.
Palantir loses legal challenge against Swiss investigative magazine (ft.com)
107 points by sschueller 2 hours ago | 16 comments
8.
Mmorpg World of ClaudeCraft, vibe coded with Fable 5 (worldofclaudecraft.com)
62 points by beatthatflight 2 hours ago | 52 comments
9.
Slightly reducing the sloppiness of AI generated front end (envs.net)
152 points by FergusArgyll 7 hours ago | 105 comments
10.
Can I Buy Your KV Cache? (arxiv.org)
23 points by MediaSquirrel 2 hours ago | 16 comments
11.
Launch HN: BitBoard (YC P25) – Analytics Workspace for Agents (bitboard.work)
29 points by arcb 5 hours ago | 17 comments
12.
Introduction to UEFI HTTP(s) Boot with QEMU/OVMF (blog.yadutaf.fr)
66 points by jtlebigot 7 hours ago | 24 comments
13.
"Don't You Just Upload It to ChatGPT?" (correresmidestino.com)
234 points by speckx 4 hours ago | 205 comments
14.
A PDF that changes based on how its read (sgaud.com)
111 points by SarthakGaud 6 hours ago | 56 comments
15.
EV demand up 50% in France and Germany since Iran war (reuters.com)
86 points by a_paddy 3 hours ago | 30 comments
16.
Cosmodial Sky Atlas (killedbyapixel.github.io)
23 points by memalign 4 hours ago | 3 comments
17.
Show HN: Turn your name into a tree in an infinite procedural shanshui landscape (landscape.bairui.dev)
4 points by subairui 2 days ago | 2 comments
18.
Where Did Earth Get Its Oceans? Maybe It Made Them Itself (quantamagazine.org)
93 points by ibobev 7 hours ago | 55 comments
19.
I Am Not a Reverse Centaur (blog.miguelgrinberg.com)
232 points by ibobev 4 hours ago | 166 comments
20.
There Is Life Before Main in Rust (grack.com)
63 points by mmastrac 1 day ago | 16 comments
21.
Maxproof (arxiv.org)
123 points by ilreb 10 hours ago | 10 comments
22.
If you are asking for human attention, demonstrate human effort (tombedor.dev)
1465 points by jjfoooo4 23 hours ago | 455 comments
23.
Hazel (YC W24) Is Hiring a Full Stack Engineer (ycombinator.com)
1 points by augustschen 9 hours ago
24.
Most Beautiful Will Ever Made (1936) (paperspast.natlib.govt.nz)
24 points by cf100clunk 4 hours ago | 9 comments
25.
A dumpster arrived behind my university's library (yalereview.org)
145 points by mooreds 8 hours ago | 132 comments
26.
Satellite images reveal Putin is preparing for war with Europe (dailymail.com)
11 points by Bender 27 minutes ago
27.
WASI 0.3 (bytecodealliance.org)
220 points by mavdol04 8 hours ago | 86 comments
28.
Show HN: StackScope – I crawled over 40k indie launches to see what they ship (stackscope.dev)
38 points by datafreak_ 7 hours ago | 12 comments
29.
Encrypted Spaces An architecture for collaborative applications (encryptedspaces.org)
62 points by _____k 10 hours ago | 9 comments
30.
Looking Forward to Postgres 19: It's About Time (pgedge.com)
128 points by xngbuilds 6 hours ago | 37 comments