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1.
CRISPR tech selectively shreds cancer cells, including "undruggable" cancers (innovativegenomics.org)
234 points by gmays 2 hours ago | 59 comments
2.
A PDF that changes based on who is reading (sgaud.com)
33 points by SarthakGaud 1 hour ago | 14 comments
3.
Keygen.music (keygen.music)
79 points by soupspaces 2 hours ago | 36 comments
4.
A dumpster arrived behind my university's library (yalereview.org)
90 points by mooreds 3 hours ago | 62 comments
5.
Slightly reducing the sloppiness of AI generated front end (envs.net)
91 points by FergusArgyll 3 hours ago | 58 comments
6.
Where Did Earth Get Its Oceans? Maybe It Made Them Itself (quantamagazine.org)
49 points by ibobev 2 hours ago | 32 comments
7.
Malware developers added nuclear and biological weapons text to to their spyware (twitter.com)
73 points by marc__1 21 hours ago | 53 comments
8.
Looking Forward to Postgres 19: It's About Time (pgedge.com)
25 points by xngbuilds 1 hour ago | 2 comments
9.
Launch HN: BitBoard (YC P25) – Analytics Workspace for Agents (bitboard.work)
8 points by arcb 1 hour ago | 4 comments
10.
Maxproof (arxiv.org)
106 points by ilreb 6 hours ago | 8 comments
11.
Introduction to UEFI HTTP(s) Boot with QEMU/OVMF (blog.yadutaf.fr)
28 points by jtlebigot 3 hours ago | 3 comments
12.
A Call to Action: Stop the FCC's KYC Regime (blog.lopp.net)
246 points by FergusArgyll 3 hours ago | 157 comments
13.
AI agent bankrupted their operator while trying to scan DN42 (lantian.pub)
1282 points by xiaoyu2006 13 hours ago | 465 comments
14.
WASI 0.3 (bytecodealliance.org)
181 points by mavdol04 4 hours ago | 71 comments
15.
How to Setup a Local Coding Agent on macOS (ikyle.me)
2 points by kkm 29 minutes ago
16.
Hazel (YC W24) Is Hiring a Full Stack Engineer (ycombinator.com)
1 points by augustschen 4 hours ago
17.
There Is Life Before Main in Rust (grack.com)
16 points by mmastrac 1 day ago | 4 comments
18.
AUR packages compromised with Infostealer and Rootkit (discourse.ifin.network)
227 points by keyle 12 hours ago | 149 comments
19.
Show HN: StackScope – I crawled over 40k indie launches to see what they ship (stackscope.dev)
17 points by datafreak_ 2 hours ago | 3 comments
20.
If you are asking for human attention, demonstrate human effort (tombedor.dev)
1346 points by jjfoooo4 19 hours ago | 431 comments
21.
Pirates, a naval warfare game inspired by Sid Meier's Pirates (piwodlaiwo.github.io)
4 points by iweczek 56 minutes ago
22.
Show HN: Script to bulk delete Claude chats from the web UI (github.com)
34 points by ML0037 2 hours ago | 12 comments
23.
Encrypted Spaces An architecture for collaborative applications (encryptedspaces.org)
37 points by _____k 5 hours ago | 4 comments
24.
New privacy frontier: Europe eyes crackdown on smart glasses (politico.com)
28 points by 1vuio0pswjnm7 1 hour ago | 5 comments
25.
How we made hit video game Prince of Persia (theguardian.com)
235 points by msephton 2 days ago | 91 comments
26.
Kimi K2.7-Code: open-source coding model with better token efficiency (huggingface.co)
320 points by nekofneko 7 hours ago | 166 comments
27.
Euro-Office, open standards, and native ODF (blog.documentfoundation.org)
46 points by ChrisArchitect 2 hours ago | 4 comments
28.
A jacket that harvests drinking water from the air (news.utexas.edu)
137 points by ilreb 19 hours ago | 88 comments
29.
Appeals court upholds FTX co-founder Sam Bankman-Fried's fraud conviction (apnews.com)
20 points by 1vuio0pswjnm7 1 hour ago | 2 comments
30.
Nobody ever gets credit for fixing problems that never happened (2001) [pdf] (web.mit.edu)
685 points by sam_bristow 17 hours ago | 227 comments