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1.
CRISPR tech selectively shreds cancer cells, including "undruggable" cancers (innovativegenomics.org)
368 points by gmays 4 hours ago | 94 comments
2.
I Am Not a Reverse Centaur (blog.miguelgrinberg.com)
93 points by ibobev 1 hour ago | 49 comments
3.
How to Setup a Local Coding Agent on macOS (ikyle.me)
71 points by kkm 1 hour ago | 21 comments
4.
Pirates, a naval warfare game inspired by Sid Meier's Pirates (piwodlaiwo.github.io)
55 points by iweczek 2 hours ago | 24 comments
5.
Malware developers added nuclear and biological weapons text to to their spyware (twitter.com)
118 points by marc__1 23 hours ago | 81 comments
6.
A PDF that changes based on how its read (sgaud.com)
69 points by SarthakGaud 2 hours ago | 31 comments
7.
Slightly reducing the sloppiness of AI generated front end (envs.net)
121 points by FergusArgyll 4 hours ago | 78 comments
8.
Looking Forward to Postgres 19: It's About Time (pgedge.com)
62 points by xngbuilds 2 hours ago | 18 comments
9.
A dumpster arrived behind my university's library (yalereview.org)
118 points by mooreds 5 hours ago | 92 comments
10.
Law Enforcement's "Warrior" Problem (2015) (harvardlawreview.org)
31 points by bookofjoe 2 hours ago | 20 comments
11.
Where Did Earth Get Its Oceans? Maybe It Made Them Itself (quantamagazine.org)
67 points by ibobev 3 hours ago | 43 comments
12.
Launch HN: BitBoard (YC P25) – Analytics Workspace for Agents (bitboard.work)
16 points by arcb 2 hours ago | 6 comments
13.
There Is Life Before Main in Rust (grack.com)
32 points by mmastrac 1 day ago | 9 comments
14.
Keygen.music (keygen.music)
102 points by soupspaces 3 hours ago | 61 comments
15.
AI agent bankrupted their operator while trying to scan DN42 (lantian.pub)
1310 points by xiaoyu2006 14 hours ago | 475 comments
16.
Introduction to UEFI HTTP(s) Boot with QEMU/OVMF (blog.yadutaf.fr)
35 points by jtlebigot 4 hours ago | 8 comments
17.
Cosmodial Sky Atlas (killedbyapixel.github.io)
8 points by memalign 1 hour ago | 1 comments
18.
Hazel (YC W24) Is Hiring a Full Stack Engineer (ycombinator.com)
1 points by augustschen 6 hours ago
19.
Maxproof (arxiv.org)
110 points by ilreb 7 hours ago | 8 comments
20.
A Call to Action: Stop the FCC's KYC Regime (blog.lopp.net)
269 points by FergusArgyll 4 hours ago | 174 comments
21.
I Won't Buy You a Coffee (hakkerman.eu)
33 points by speckx 48 minutes ago | 29 comments
22.
WASI 0.3 (bytecodealliance.org)
195 points by mavdol04 5 hours ago | 80 comments
23.
A Peter Thiel-Backed Tribunal Is Putting Journalists on Trial (hollywoodreporter.com)
30 points by cdrnsf 44 minutes ago | 5 comments
24.
Show HN: StackScope – I crawled over 40k indie launches to see what they ship (stackscope.dev)
27 points by datafreak_ 3 hours ago | 8 comments
25.
If you are asking for human attention, demonstrate human effort (tombedor.dev)
1390 points by jjfoooo4 20 hours ago | 440 comments
26.
"Don't You Just Upload It to ChatGPT?" (correresmidestino.com)
90 points by speckx 1 hour ago | 88 comments
27.
New privacy frontier: Europe eyes crackdown on smart glasses (politico.com)
51 points by 1vuio0pswjnm7 2 hours ago | 30 comments
28.
How we made hit video game Prince of Persia (theguardian.com)
249 points by msephton 2 days ago | 98 comments
29.
Encrypted Spaces An architecture for collaborative applications (encryptedspaces.org)
46 points by _____k 7 hours ago | 5 comments
30.
Show HN: Script to bulk delete Claude chats from the web UI (github.com)
41 points by ML0037 4 hours ago | 12 comments