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1. CRISPR tech selectively shreds cancer cells, including "undruggable" cancers (innovativegenomics.org)
342 points by gmays 3 hours ago | 89 comments
2. I Am Not a Reverse Centaur (blog.miguelgrinberg.com)
69 points by ibobev 1 hour ago | 25 comments
3. How to Setup a Local Coding Agent on macOS (ikyle.me)
45 points by kkm 1 hour ago | 11 comments
4. Pirates, a naval warfare game inspired by Sid Meier's Pirates (piwodlaiwo.github.io)
42 points by iweczek 1 hour ago | 18 comments
5. A PDF that changes based on how its read (sgaud.com)
66 points by SarthakGaud 2 hours ago | 30 comments
6. Slightly reducing the sloppiness of AI generated front end (envs.net)
115 points by FergusArgyll 4 hours ago | 74 comments
7. Looking Forward to Postgres 19: It's About Time (pgedge.com)
53 points by xngbuilds 2 hours ago | 17 comments
8. Malware developers added nuclear and biological weapons text to to their spyware (twitter.com)
104 points by marc__1 22 hours ago | 79 comments
9. A dumpster arrived behind my university's library (yalereview.org)
112 points by mooreds 4 hours ago | 86 comments
10. Where Did Earth Get Its Oceans? Maybe It Made Them Itself (quantamagazine.org)
64 points by ibobev 3 hours ago | 41 comments
11. Tesla Full Self Driving uses bicycle lane in official Denmark approval video (politiken.dk)
79 points by Veserv 1 hour ago | 21 comments
12. Launch HN: BitBoard (YC P25) – Analytics Workspace for Agents (bitboard.work)
15 points by arcb 2 hours ago | 4 comments
13. There Is Life Before Main in Rust (grack.com)
29 points by mmastrac 1 day ago | 8 comments
14. Cosmodial Sky Atlas (killedbyapixel.github.io)
6 points by memalign 43 minutes ago | 1 comments
15. AI agent bankrupted their operator while trying to scan DN42 (lantian.pub)
1299 points by xiaoyu2006 14 hours ago | 473 comments
16. Introduction to UEFI HTTP(s) Boot with QEMU/OVMF (blog.yadutaf.fr)
33 points by jtlebigot 4 hours ago | 8 comments
17. Keygen.music (keygen.music)
97 points by soupspaces 3 hours ago | 58 comments
18. Hazel (YC W24) Is Hiring a Full Stack Engineer (ycombinator.com)
1 points by augustschen 5 hours ago
19. Maxproof (arxiv.org)
108 points by ilreb 7 hours ago | 8 comments
20. A Call to Action: Stop the FCC's KYC Regime (blog.lopp.net)
266 points by FergusArgyll 4 hours ago | 171 comments
21. Law Enforcement's "Warrior" Problem (2015) (harvardlawreview.org)
22 points by bookofjoe 1 hour ago | 13 comments
22. "Don't You Just Upload It to ChatGPT?" (correresmidestino.com)
78 points by speckx 1 hour ago | 74 comments
23. WASI 0.3 (bytecodealliance.org)
191 points by mavdol04 5 hours ago | 76 comments
24. I Won't Buy You a Coffee (hakkerman.eu)
18 points by speckx 26 minutes ago | 13 comments
25. A Peter Thiel-Backed Tribunal Is Putting Journalists on Trial (hollywoodreporter.com)
7 points by cdrnsf 23 minutes ago | 1 comments
26. If you are asking for human attention, demonstrate human effort (tombedor.dev)
1378 points by jjfoooo4 20 hours ago | 439 comments
27. New privacy frontier: Europe eyes crackdown on smart glasses (politico.com)
43 points by 1vuio0pswjnm7 2 hours ago | 27 comments
28. Encrypted Spaces An architecture for collaborative applications (encryptedspaces.org)
44 points by _____k 6 hours ago | 5 comments
29. How we made hit video game Prince of Persia (theguardian.com)
246 points by msephton 2 days ago | 94 comments
30. Show HN: StackScope – I crawled over 40k indie launches to see what they ship (stackscope.dev)
24 points by datafreak_ 3 hours ago | 7 comments