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1.
CRISPR tech selectively shreds cancer cells, including "undruggable" cancers (innovativegenomics.org)
326 points by gmays 3 hours ago | 79 comments
2.
I Am Not a Reverse Centaur (blog.miguelgrinberg.com)
50 points by ibobev 51 minutes ago | 7 comments
3.
A PDF that changes based on how its read (sgaud.com)
64 points by SarthakGaud 2 hours ago | 28 comments
4.
How to Setup a Local Coding Agent on macOS (ikyle.me)
22 points by kkm 1 hour ago | 6 comments
5.
Slightly reducing the sloppiness of AI generated front end (envs.net)
112 points by FergusArgyll 3 hours ago | 67 comments
6.
Pirates, a naval warfare game inspired by Sid Meier's Pirates (piwodlaiwo.github.io)
32 points by iweczek 1 hour ago | 9 comments
7.
Looking Forward to Postgres 19: It's About Time (pgedge.com)
49 points by xngbuilds 2 hours ago | 15 comments
8.
A dumpster arrived behind my university's library (yalereview.org)
110 points by mooreds 4 hours ago | 78 comments
9.
Where Did Earth Get Its Oceans? Maybe It Made Them Itself (quantamagazine.org)
62 points by ibobev 3 hours ago | 39 comments
10.
Malware developers added nuclear and biological weapons text to to their spyware (twitter.com)
92 points by marc__1 22 hours ago | 71 comments
11.
Keygen.music (keygen.music)
94 points by soupspaces 3 hours ago | 54 comments
12.
Launch HN: BitBoard (YC P25) – Analytics Workspace for Agents (bitboard.work)
15 points by arcb 1 hour ago | 4 comments
13.
Tesla Full Self Driving uses bicycle lane in official Denmark approval video (politiken.dk)
45 points by Veserv 55 minutes ago | 8 comments
14.
There Is Life Before Main in Rust (grack.com)
25 points by mmastrac 1 day ago | 7 comments
15.
"Don't You Just Upload It to ChatGPT?" (correresmidestino.com)
63 points by speckx 52 minutes ago | 57 comments
16.
Maxproof (arxiv.org)
108 points by ilreb 6 hours ago | 8 comments
17.
Introduction to UEFI HTTP(s) Boot with QEMU/OVMF (blog.yadutaf.fr)
32 points by jtlebigot 3 hours ago | 6 comments
18.
Hazel (YC W24) Is Hiring a Full Stack Engineer (ycombinator.com)
1 points by augustschen 5 hours ago
19.
AI agent bankrupted their operator while trying to scan DN42 (lantian.pub)
1297 points by xiaoyu2006 14 hours ago | 472 comments
20.
Cosmodial Sky Atlas (killedbyapixel.github.io)
4 points by memalign 24 minutes ago
21.
A Call to Action: Stop the FCC's KYC Regime (blog.lopp.net)
262 points by FergusArgyll 4 hours ago | 166 comments
22.
WASI 0.3 (bytecodealliance.org)
190 points by mavdol04 4 hours ago | 75 comments
23.
Law Enforcement's "Warrior" Problem (2015) (harvardlawreview.org)
18 points by bookofjoe 1 hour ago | 8 comments
24.
If you are asking for human attention, demonstrate human effort (tombedor.dev)
1370 points by jjfoooo4 19 hours ago | 437 comments
25.
New privacy frontier: Europe eyes crackdown on smart glasses (politico.com)
41 points by 1vuio0pswjnm7 2 hours ago | 21 comments
26.
Show HN: StackScope – I crawled over 40k indie launches to see what they ship (stackscope.dev)
22 points by datafreak_ 3 hours ago | 6 comments
27.
Show HN: Script to bulk delete Claude chats from the web UI (github.com)
39 points by ML0037 3 hours ago | 14 comments
28.
Encrypted Spaces An architecture for collaborative applications (encryptedspaces.org)
42 points by _____k 6 hours ago | 5 comments
29.
How we made hit video game Prince of Persia (theguardian.com)
244 points by msephton 2 days ago | 92 comments
30.
AUR packages compromised with Infostealer and Rootkit (discourse.ifin.network)
239 points by keyle 12 hours ago | 169 comments