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1. CRISPR tech selectively shreds cancer cells, including "undruggable" cancers (innovativegenomics.org)
597 points by gmays 7 hours ago | 159 comments
2. Swift at Apple: Migrating the TrueType hinting interpreter (swift.org)
75 points by DASD 2 hours ago | 30 comments
3. How to setup a local coding agent on macOS (ikyle.me)
185 points by kkm 5 hours ago | 61 comments
4. Malware developers added nuclear and biological weapons text to to their spyware (twitter.com)
236 points by marc__1 1 day ago | 162 comments
5. Pirates, a naval warfare game inspired by Sid Meier's Pirates (piwodlaiwo.github.io)
156 points by iweczek 5 hours ago | 67 comments
6. Palantir loses legal challenge against Swiss investigative magazine (ft.com)
100 points by sschueller 2 hours ago | 15 comments
7. Congress Just Rushed Through a Disastrous Copyright Office Overhaul (eff.org)
39 points by Cider9986 1 day ago | 1 comments
8. Mmorpg World of ClaudeCraft, vibe coded with Fable 5 (worldofclaudecraft.com)
57 points by beatthatflight 2 hours ago | 51 comments
9. Slightly reducing the sloppiness of AI generated front end (envs.net)
151 points by FergusArgyll 7 hours ago | 104 comments
10. Can I Buy Your KV Cache? (arxiv.org)
23 points by MediaSquirrel 2 hours ago | 14 comments
11. Launch HN: BitBoard (YC P25) – Analytics Workspace for Agents (bitboard.work)
29 points by arcb 5 hours ago | 17 comments
12. Introduction to UEFI HTTP(s) Boot with QEMU/OVMF (blog.yadutaf.fr)
66 points by jtlebigot 7 hours ago | 22 comments
13. "Don't You Just Upload It to ChatGPT?" (correresmidestino.com)
231 points by speckx 4 hours ago | 204 comments
14. Where Did Earth Get Its Oceans? Maybe It Made Them Itself (quantamagazine.org)
92 points by ibobev 7 hours ago | 55 comments
15. Show HN: Turn your name into a tree in an infinite procedural shanshui landscape (landscape.bairui.dev)
4 points by subairui 2 days ago | 2 comments
16. A PDF that changes based on how its read (sgaud.com)
109 points by SarthakGaud 6 hours ago | 56 comments
17. EV demand up 50% in France and Germany since Iran war (reuters.com)
82 points by a_paddy 3 hours ago | 27 comments
18. Cosmodial Sky Atlas (killedbyapixel.github.io)
23 points by memalign 4 hours ago | 3 comments
19. I Am Not a Reverse Centaur (blog.miguelgrinberg.com)
232 points by ibobev 4 hours ago | 164 comments
20. There Is Life Before Main in Rust (grack.com)
62 points by mmastrac 1 day ago | 16 comments
21. Maxproof (arxiv.org)
123 points by ilreb 10 hours ago | 10 comments
22. Hazel (YC W24) Is Hiring a Full Stack Engineer (ycombinator.com)
1 points by augustschen 9 hours ago
23. If you are asking for human attention, demonstrate human effort (tombedor.dev)
1462 points by jjfoooo4 23 hours ago | 455 comments
24. Most Beautiful Will Ever Made (1936) (paperspast.natlib.govt.nz)
21 points by cf100clunk 4 hours ago | 9 comments
25. A dumpster arrived behind my university's library (yalereview.org)
145 points by mooreds 8 hours ago | 132 comments
26. Show HN: StackScope – I crawled over 40k indie launches to see what they ship (stackscope.dev)
38 points by datafreak_ 7 hours ago | 12 comments
27. WASI 0.3 (bytecodealliance.org)
218 points by mavdol04 8 hours ago | 86 comments
28. Encrypted Spaces An architecture for collaborative applications (encryptedspaces.org)
61 points by _____k 10 hours ago | 9 comments
29. Looking Forward to Postgres 19: It's About Time (pgedge.com)
128 points by xngbuilds 5 hours ago | 37 comments
30. A Call to Action: Stop the FCC's KYC Regime (blog.lopp.net)
303 points by FergusArgyll 8 hours ago | 203 comments