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1. CRISPR tech selectively shreds cancer cells, including "undruggable" cancers (innovativegenomics.org)
627 points by gmays 7 hours ago | 165 comments
2. Swift at Apple: Migrating the TrueType hinting interpreter (swift.org)
88 points by DASD 3 hours ago | 36 comments
3. Renault: Electric motors with no rare earths (renaultgroup.com)
16 points by bestouff 1 hour ago | 1 comments
4. How to setup a local coding agent on macOS (ikyle.me)
201 points by kkm 5 hours ago | 64 comments
5. Malware developers added nuclear and biological weapons text to to their spyware (twitter.com)
255 points by marc__1 1 day ago | 173 comments
6. Pirates, a naval warfare game inspired by Sid Meier's Pirates (piwodlaiwo.github.io)
164 points by iweczek 6 hours ago | 69 comments
7. Congress just rushed through a disastrous copyright office overhaul (eff.org)
65 points by Cider9986 1 day ago | 4 comments
8. Palantir loses legal challenge against Swiss investigative magazine (ft.com)
114 points by sschueller 2 hours ago | 21 comments
9. Twenty One Zero-Days in FFmpeg (depthfirst.com)
12 points by redbell 54 minutes ago | 3 comments
10. Launch HN: BitBoard (YC P25) – Analytics Workspace for Agents (bitboard.work)
30 points by arcb 6 hours ago | 17 comments
11. Can I Buy Your KV Cache? (arxiv.org)
25 points by MediaSquirrel 2 hours ago | 20 comments
12. "Don't You Just Upload It to ChatGPT?" (correresmidestino.com)
248 points by speckx 5 hours ago | 212 comments
13. Mmorpg World of ClaudeCraft, vibe coded with Fable 5 (worldofclaudecraft.com)
72 points by beatthatflight 2 hours ago | 64 comments
14. Slightly reducing the sloppiness of AI generated front end (envs.net)
154 points by FergusArgyll 8 hours ago | 108 comments
15. Introduction to UEFI HTTP(s) Boot with QEMU/OVMF (blog.yadutaf.fr)
67 points by jtlebigot 8 hours ago | 25 comments
16. EV demand up 50% in France and Germany since Iran war (reuters.com)
95 points by a_paddy 4 hours ago | 44 comments
17. Adaptive PDFs (sgaud.com)
112 points by SarthakGaud 6 hours ago | 59 comments
18. Where Did Earth Get Its Oceans? Maybe It Made Them Itself (quantamagazine.org)
93 points by ibobev 7 hours ago | 56 comments
19. Cosmodial Sky Atlas (killedbyapixel.github.io)
24 points by memalign 4 hours ago | 4 comments
20. If you are asking for human attention, demonstrate human effort (tombedor.dev)
1475 points by jjfoooo4 1 day ago | 455 comments
21. Maxproof (arxiv.org)
123 points by ilreb 11 hours ago | 10 comments
22. There Is Life Before Main in Rust (grack.com)
64 points by mmastrac 1 day ago | 17 comments
23. Show HN: Turn your name into a tree in an infinite procedural shanshui landscape (landscape.bairui.dev)
6 points by subairui 2 days ago | 2 comments
24. Hazel (YC W24) Is Hiring a Full Stack Engineer (ycombinator.com)
1 points by augustschen 9 hours ago
25. I Am Not a Reverse Centaur (blog.miguelgrinberg.com)
234 points by ibobev 5 hours ago | 168 comments
26. Most Beautiful Will Ever Made (1936) (paperspast.natlib.govt.nz)
26 points by cf100clunk 4 hours ago | 12 comments
27. /architect: Reduce Fable tokens by 80%, Fable orchestrates/reviews, Codex builds (github.com)
5 points by DanMcInerney 2 hours ago
28. A dumpster arrived behind my university's library (yalereview.org)
146 points by mooreds 8 hours ago | 135 comments
29. Show HN: StackScope – I crawled over 40k indie launches to see what they ship (stackscope.dev)
39 points by datafreak_ 7 hours ago | 12 comments
30. WASI 0.3 (bytecodealliance.org)
224 points by mavdol04 9 hours ago | 86 comments