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1. CRISPR tech selectively shreds cancer cells, including "undruggable" cancers (innovativegenomics.org)
321 points by gmays 3 hours ago | 75 comments
2. I Am Not a Reverse Centaur (blog.miguelgrinberg.com)
42 points by ibobev 48 minutes ago | 4 comments
3. A PDF that changes based on how its read (sgaud.com)
63 points by SarthakGaud 2 hours ago | 27 comments
4. How to Setup a Local Coding Agent on macOS (ikyle.me)
22 points by kkm 1 hour ago | 6 comments
5. Slightly reducing the sloppiness of AI generated front end (envs.net)
112 points by FergusArgyll 3 hours ago | 65 comments
6. Pirates, a naval warfare game inspired by Sid Meier's Pirates (piwodlaiwo.github.io)
26 points by iweczek 1 hour ago | 4 comments
7. Looking Forward to Postgres 19: It's About Time (pgedge.com)
49 points by xngbuilds 1 hour ago | 15 comments
8. A dumpster arrived behind my university's library (yalereview.org)
108 points by mooreds 4 hours ago | 75 comments
9. Where Did Earth Get Its Oceans? Maybe It Made Them Itself (quantamagazine.org)
62 points by ibobev 3 hours ago | 38 comments
10. Malware developers added nuclear and biological weapons text to to their spyware (twitter.com)
89 points by marc__1 22 hours ago | 71 comments
11. Keygen.music (keygen.music)
92 points by soupspaces 3 hours ago | 52 comments
12. Launch HN: BitBoard (YC P25) – Analytics Workspace for Agents (bitboard.work)
15 points by arcb 1 hour ago | 4 comments
13. There Is Life Before Main in Rust (grack.com)
25 points by mmastrac 1 day ago | 7 comments
14. Tesla Full Self Driving uses bicycle lane in official Denmark approval video (politiken.dk)
45 points by Veserv 52 minutes ago | 8 comments
15. "Don't You Just Upload It to ChatGPT?" (correresmidestino.com)
63 points by speckx 49 minutes ago | 57 comments
16. Maxproof (arxiv.org)
108 points by ilreb 6 hours ago | 8 comments
17. Hazel (YC W24) Is Hiring a Full Stack Engineer (ycombinator.com)
1 points by augustschen 5 hours ago
18. Introduction to UEFI HTTP(s) Boot with QEMU/OVMF (blog.yadutaf.fr)
32 points by jtlebigot 3 hours ago | 6 comments
19. AI agent bankrupted their operator while trying to scan DN42 (lantian.pub)
1295 points by xiaoyu2006 13 hours ago | 472 comments
20. Cosmodial Sky Atlas (killedbyapixel.github.io)
4 points by memalign 21 minutes ago
21. A Call to Action: Stop the FCC's KYC Regime (blog.lopp.net)
262 points by FergusArgyll 4 hours ago | 166 comments
22. WASI 0.3 (bytecodealliance.org)
189 points by mavdol04 4 hours ago | 75 comments
23. Law Enforcement's "Warrior" Problem (2015) (harvardlawreview.org)
18 points by bookofjoe 1 hour ago | 8 comments
24. If you are asking for human attention, demonstrate human effort (tombedor.dev)
1367 points by jjfoooo4 19 hours ago | 435 comments
25. New privacy frontier: Europe eyes crackdown on smart glasses (politico.com)
41 points by 1vuio0pswjnm7 2 hours ago | 21 comments
26. Show HN: StackScope – I crawled over 40k indie launches to see what they ship (stackscope.dev)
22 points by datafreak_ 3 hours ago | 6 comments
27. Show HN: Script to bulk delete Claude chats from the web UI (github.com)
38 points by ML0037 3 hours ago | 14 comments
28. Encrypted Spaces An architecture for collaborative applications (encryptedspaces.org)
42 points by _____k 6 hours ago | 5 comments
29. How we made hit video game Prince of Persia (theguardian.com)
240 points by msephton 2 days ago | 92 comments
30. AUR packages compromised with Infostealer and Rootkit (discourse.ifin.network)
237 points by keyle 12 hours ago | 165 comments