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Why the Human Genome's Tangled Physicality May Confound AI (quantamagazine.org)
5 points by tzury 39 days ago
1 comments

higher order [secondary,tertiary] structure is almost subjective, while primary [sequence] structure is a data representation scheme.

the DNA is also a mechanical device that does molecular work in order to generate a transcript. molecular strain, and torsion are major considerations in the final functional distribution of expression domains.

2' and 3' topologically associated domains[TAD]