20 years of serial mouse cloning fails in 58th generation

Y	Hacker News new \| ask \| show \| jobs

	20 years of serial mouse cloning fails in 58th generation (nature.com)
	8 points by warbaker 51 days ago

2 comments

Title: Limitations of serial cloning in mammals

From a month ago -

Reuters Mouse study shows repeated cloning causes grave genetic mutations (6 points) https://news.ycombinator.com/item?id=47510677

Nature Can a mouse be cloned indefinitely? (6 points) https://news.ycombinator.com/item?id=47515624

I was so very confused by the title, thinking they were talking about computer mice

I knew serial mice were difficult to work with, but didn't realize we were still trying to make them better in 2026.