Good Q. Early tracking seems to indicate there's a good chance, but one thing to consider is that Avengers more than doubled BP budget so matching revenue is one thing. Being as successful will be even harder.
The big question is if the audience is getting fatigued on Avengers or excited about next chapter in the overall story; since BP was of the cannon but also decidedly new and different. So far, trailer interaction and presale numbers-wise seems like people are excited.
Will it beat Black Panther?