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1.
CRISPR tech selectively shreds cancer cells, including "undruggable" cancers (innovativegenomics.org)
387 points by gmays 4 hours ago | 99 comments
2.
I Am Not a Reverse Centaur (blog.miguelgrinberg.com)
100 points by ibobev 1 hour ago | 64 comments
3.
How to Setup a Local Coding Agent on macOS (ikyle.me)
73 points by kkm 1 hour ago | 21 comments
4.
Malware developers added nuclear and biological weapons text to to their spyware (twitter.com)
123 points by marc__1 23 hours ago | 81 comments
5.
Pirates, a naval warfare game inspired by Sid Meier's Pirates (piwodlaiwo.github.io)
62 points by iweczek 2 hours ago | 26 comments
6.
A PDF that changes based on how its read (sgaud.com)
74 points by SarthakGaud 2 hours ago | 33 comments
7.
Slightly reducing the sloppiness of AI generated front end (envs.net)
124 points by FergusArgyll 4 hours ago | 80 comments
8.
Looking Forward to Postgres 19: It's About Time (pgedge.com)
63 points by xngbuilds 2 hours ago | 18 comments
9.
A dumpster arrived behind my university's library (yalereview.org)
123 points by mooreds 5 hours ago | 96 comments
10.
Law Enforcement's "Warrior" Problem (2015) (harvardlawreview.org)
33 points by bookofjoe 2 hours ago | 24 comments
11.
Where Did Earth Get Its Oceans? Maybe It Made Them Itself (quantamagazine.org)
71 points by ibobev 3 hours ago | 43 comments
12.
There Is Life Before Main in Rust (grack.com)
34 points by mmastrac 1 day ago | 10 comments
13.
A Peter Thiel-Backed Tribunal Is Putting Journalists on Trial (hollywoodreporter.com)
47 points by cdrnsf 51 minutes ago | 8 comments
14.
Launch HN: BitBoard (YC P25) – Analytics Workspace for Agents (bitboard.work)
17 points by arcb 2 hours ago | 6 comments
15.
AI agent bankrupted their operator while trying to scan DN42 (lantian.pub)
1321 points by xiaoyu2006 14 hours ago | 475 comments
16.
Introduction to UEFI HTTP(s) Boot with QEMU/OVMF (blog.yadutaf.fr)
36 points by jtlebigot 4 hours ago | 8 comments
17.
Maxproof (arxiv.org)
114 points by ilreb 7 hours ago | 8 comments
18.
Cosmodial Sky Atlas (killedbyapixel.github.io)
10 points by memalign 1 hour ago | 1 comments
19.
Hazel (YC W24) Is Hiring a Full Stack Engineer (ycombinator.com)
1 points by augustschen 6 hours ago
20.
A Call to Action: Stop the FCC's KYC Regime (blog.lopp.net)
273 points by FergusArgyll 4 hours ago | 175 comments
21.
I Won't Buy You a Coffee (hakkerman.eu)
41 points by speckx 54 minutes ago | 33 comments
22.
WASI 0.3 (bytecodealliance.org)
198 points by mavdol04 5 hours ago | 80 comments
23.
Show HN: StackScope – I crawled over 40k indie launches to see what they ship (stackscope.dev)
28 points by datafreak_ 4 hours ago | 8 comments
24.
Keygen.music (keygen.music)
106 points by soupspaces 3 hours ago | 62 comments
25.
If you are asking for human attention, demonstrate human effort (tombedor.dev)
1394 points by jjfoooo4 20 hours ago | 440 comments
26.
New privacy frontier: Europe eyes crackdown on smart glasses (politico.com)
52 points by 1vuio0pswjnm7 2 hours ago | 31 comments
27.
How we made hit video game Prince of Persia (theguardian.com)
249 points by msephton 2 days ago | 101 comments
28.
Encrypted Spaces An architecture for collaborative applications (encryptedspaces.org)
49 points by _____k 7 hours ago | 5 comments
29.
"Don't You Just Upload It to ChatGPT?" (correresmidestino.com)
92 points by speckx 1 hour ago | 89 comments
30.
Show HN: Script to bulk delete Claude chats from the web UI (github.com)
43 points by ML0037 4 hours ago | 14 comments